Malignant peripheral nerve sheath tumours in magnetic resonance imaging : primary and recurrent tumour appearance, post-treatment changes, and metastases

2020
journal article
article
cris.lastimport.wos2024-04-10T00:53:47Z
dc.abstract.enPurpose: To analyse the appearance of primary and recurrent malignant peripheral nerve sheath tumours (MPNSTs) in magnetic resonance imaging (MRI) with a focus on configuration, and to assess the occurrence of loco-regional post-treatment changes and metastases during post-treatment follow-up. Material and methods: Twenty patients with histologically proven MPNST underwent post-treatment 1.5 T MRI. Primary and recurrent MPNSTs were examined for configuration, contrast enhancement, extent, and signal intensity in MRI. Loco-regional post-treatment changes and information on metastases were extracted from the follow-up. Results: MPNSTs occurred most often in the extremities (p = 0.006). Twenty per cent (n = 4) of the patients developed recurrences, with a total of 24 lesions. Recurrent MPNSTs were significantly smaller than primary MPNSTs (p = 0.003). Primary MPNSTs mostly occurred unifocally as multilobulated or ovoid and heterogeneous lesions with mostly well-defined borders. Recurrent MPNSTs purely occurred multifocally as mostly nodular (p < 0.001), multilobulated, or ovoid lesions. 80%, 65% and 30% of the patients showed post-treatment subcutaneous oedema (p = 0.002 to 0.03), muscle oedema (p = 0.02), and seroma, respectively. Twenty-five per cent (n = 5) of patients presented metastases during follow-up. The relative risk in patients with recurrences to develop lung or lymph node metastases is eightfold (p = 0.056). Conclusions: While primary MPNSTs mostly appear unifocally as multilobulated or ovoid lesions, recurrent MPNSTs purely occur multifocally as mostly nodular lesions. Subcutaneous and muscle oedema are very common locoregional post-treatment changes. Patients with recurrences have a higher risk for lung and lymph node metastases.pl
dc.contributor.authorSedaghat, Sampl
dc.contributor.authorSchmitz, Frederickpl
dc.contributor.authorMartin, Grözingerpl
dc.contributor.authorSedaghat, Mayapl
dc.date.accessioned2020-07-08T08:25:09Z
dc.date.available2020-07-08T08:25:09Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e201pl
dc.description.physicale196-e201pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume85pl
dc.identifier.doi10.5114/pjr.2020.94687pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/165417
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enrecurrencepl
dc.subject.enMRIpl
dc.subject.enmetastasespl
dc.subject.enoedemapl
dc.subject.enmalignant peripheral nerve sheath tumourpl
dc.subject.enappearancepl
dc.subtypeArticlepl
dc.titleMalignant peripheral nerve sheath tumours in magnetic resonance imaging : primary and recurrent tumour appearance, post-treatment changes, and metastasespl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-10T00:53:47Z
dc.abstract.enpl
Purpose: To analyse the appearance of primary and recurrent malignant peripheral nerve sheath tumours (MPNSTs) in magnetic resonance imaging (MRI) with a focus on configuration, and to assess the occurrence of loco-regional post-treatment changes and metastases during post-treatment follow-up. Material and methods: Twenty patients with histologically proven MPNST underwent post-treatment 1.5 T MRI. Primary and recurrent MPNSTs were examined for configuration, contrast enhancement, extent, and signal intensity in MRI. Loco-regional post-treatment changes and information on metastases were extracted from the follow-up. Results: MPNSTs occurred most often in the extremities (p = 0.006). Twenty per cent (n = 4) of the patients developed recurrences, with a total of 24 lesions. Recurrent MPNSTs were significantly smaller than primary MPNSTs (p = 0.003). Primary MPNSTs mostly occurred unifocally as multilobulated or ovoid and heterogeneous lesions with mostly well-defined borders. Recurrent MPNSTs purely occurred multifocally as mostly nodular (p < 0.001), multilobulated, or ovoid lesions. 80%, 65% and 30% of the patients showed post-treatment subcutaneous oedema (p = 0.002 to 0.03), muscle oedema (p = 0.02), and seroma, respectively. Twenty-five per cent (n = 5) of patients presented metastases during follow-up. The relative risk in patients with recurrences to develop lung or lymph node metastases is eightfold (p = 0.056). Conclusions: While primary MPNSTs mostly appear unifocally as multilobulated or ovoid lesions, recurrent MPNSTs purely occur multifocally as mostly nodular lesions. Subcutaneous and muscle oedema are very common locoregional post-treatment changes. Patients with recurrences have a higher risk for lung and lymph node metastases.
dc.contributor.authorpl
Sedaghat, Sam
dc.contributor.authorpl
Schmitz, Frederick
dc.contributor.authorpl
Martin, Grözinger
dc.contributor.authorpl
Sedaghat, Maya
dc.date.accessioned
2020-07-08T08:25:09Z
dc.date.available
2020-07-08T08:25:09Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. e201
dc.description.physicalpl
e196-e201
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
85
dc.identifier.doipl
10.5114/pjr.2020.94687
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/165417
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
recurrence
dc.subject.enpl
MRI
dc.subject.enpl
metastases
dc.subject.enpl
oedema
dc.subject.enpl
malignant peripheral nerve sheath tumour
dc.subject.enpl
appearance
dc.subtypepl
Article
dc.titlepl
Malignant peripheral nerve sheath tumours in magnetic resonance imaging : primary and recurrent tumour appearance, post-treatment changes, and metastases
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

* The migration of download and view statistics prior to the date of April 8, 2024 is in progress.

Views
45
Views per month
Views per city
Dublin
6
Ashburn
3
Helsinki
2
Lomé
2
Sofia
2
Wroclaw
2
Brussels
1
Falkenstein
1
San Jose
1
Szczecin
1
Downloads
sedaghat_schmitz_grozinger_sedaghat_malignant_peripheral_nerve_sheath_tumours_2020.pdf
5