Photodynamic activity of platinum(IV) chloride surface-modified irradiated with visible light

2008
journal article
article
49
cris.lastimport.wos2024-04-09T21:02:59Z
dc.abstract.enThe visible light-induced phototoxicity of titanium dioxide modified with platinum(IV) chloride complexes, $[TiO_{2}/PtCl_{4}]$, was tested. In vitro experiments with the mouse melanoma cells (S-91) have demonstrated phototoxicity of the $[TiO_{2}/PtCl_{4}]$ material. Detection of efficiently generated various reactive oxygen species $(\cdot OH, O_{2}\cdot-, H_{2}O_{2}, ^{1}\textrm{O}_{2})$ and also reactive chlorine species has proven the photodynamic activity of the tested material, induced by visible light ( $\lambda$ > 455 nm). The cellular death (recognized as a necrosis) is a result of the cell membrane peroxidation.pl
dc.affiliationWydział Chemii : Zakład Chemii Nieorganicznejpl
dc.affiliationWydział Biochemii, Biofizyki i Biotechnologii : Zakład Biofizykipl
dc.contributor.authorKyzioł, Agnieszka - 147927 pl
dc.contributor.authorStochel, Grażyna - 132108 pl
dc.contributor.authorWolnicka-Głubisz, Agnieszka - 132724 pl
dc.contributor.authorUrbańska, Krystyna - 132487 pl
dc.contributor.authorKisch, Horstpl
dc.contributor.authorMacyk, Wojciech - 130162 pl
dc.date.accessioned2015-09-16T13:02:31Z
dc.date.available2015-09-16T13:02:31Z
dc.date.issued2008pl
dc.description.additionalNa publikacji autorka Kyzioł Agnieszka podpisana jako Jańczyk Agnieszka.pl
dc.description.number6pl
dc.description.physical1120-1130pl
dc.description.volume44pl
dc.identifier.doi10.1016/j.freeradbiomed.2007.12.019pl
dc.identifier.eissn1873-4596pl
dc.identifier.issn0891-5849pl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/15697
dc.languageengpl
dc.language.containerengpl
dc.rightsDodaję tylko opis bibliograficzny*
dc.rights.licencebez licencji
dc.rights.uri*
dc.subject.enreactive oxygen speciespl
dc.subject.enphotocatalysispl
dc.subject.entitanium dioxidepl
dc.subject.enphototoxicitypl
dc.subject.enphotodynamic therapypl
dc.subject.enmouse melanomapl
dc.subtypeArticlepl
dc.titlePhotodynamic activity of platinum(IV) chloride surface-modified $TiO_{2}$ irradiated with visible lightpl
dc.title.journalFree Radical Biology and Medicinepl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T21:02:59Z
dc.abstract.enpl
The visible light-induced phototoxicity of titanium dioxide modified with platinum(IV) chloride complexes, $[TiO_{2}/PtCl_{4}]$, was tested. In vitro experiments with the mouse melanoma cells (S-91) have demonstrated phototoxicity of the $[TiO_{2}/PtCl_{4}]$ material. Detection of efficiently generated various reactive oxygen species $(\cdot OH, O_{2}\cdot-, H_{2}O_{2}, ^{1}\textrm{O}_{2})$ and also reactive chlorine species has proven the photodynamic activity of the tested material, induced by visible light ( $\lambda$ > 455 nm). The cellular death (recognized as a necrosis) is a result of the cell membrane peroxidation.
dc.affiliationpl
Wydział Chemii : Zakład Chemii Nieorganicznej
dc.affiliationpl
Wydział Biochemii, Biofizyki i Biotechnologii : Zakład Biofizyki
dc.contributor.authorpl
Kyzioł, Agnieszka - 147927
dc.contributor.authorpl
Stochel, Grażyna - 132108
dc.contributor.authorpl
Wolnicka-Głubisz, Agnieszka - 132724
dc.contributor.authorpl
Urbańska, Krystyna - 132487
dc.contributor.authorpl
Kisch, Horst
dc.contributor.authorpl
Macyk, Wojciech - 130162
dc.date.accessioned
2015-09-16T13:02:31Z
dc.date.available
2015-09-16T13:02:31Z
dc.date.issuedpl
2008
dc.description.additionalpl
Na publikacji autorka Kyzioł Agnieszka podpisana jako Jańczyk Agnieszka.
dc.description.numberpl
6
dc.description.physicalpl
1120-1130
dc.description.volumepl
44
dc.identifier.doipl
10.1016/j.freeradbiomed.2007.12.019
dc.identifier.eissnpl
1873-4596
dc.identifier.issnpl
0891-5849
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/15697
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Dodaję tylko opis bibliograficzny
dc.rights.licence
bez licencji
dc.rights.uri*
dc.subject.enpl
reactive oxygen species
dc.subject.enpl
photocatalysis
dc.subject.enpl
titanium dioxide
dc.subject.enpl
phototoxicity
dc.subject.enpl
photodynamic therapy
dc.subject.enpl
mouse melanoma
dc.subtypepl
Article
dc.titlepl
Photodynamic activity of platinum(IV) chloride surface-modified $TiO_{2}$ irradiated with visible light
dc.title.journalpl
Free Radical Biology and Medicine
dc.typepl
JournalArticle
dspace.entity.type
Publication

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