Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides

2012
journal article
article
1
cris.lastimport.wos2024-04-09T22:09:45Z
dc.abstract.enBinding modes of a dibenzotetraaza[14]annulene (DBTAA) derivative with synthetic nucleic acids were studied using surface-enhanced Raman spectroscopy (SERS). Changes in SERS intensity and appearance of new bands in spectra were attributed to different complexes formed between the DBTAA molecules and DNA/RNA polynucleotides. A decrease in intensity pointed to intercalation as the dominant binding mode of the annulene derivative with poly dGdC-poly dGdC and poly rA-poly rU, whereas new bands in the spectra at 735 cm−1 and 1345 cm−1 revealed binding within the minor groove of poly dAdT-poly dAdT. When all the dominant binding sites were occupied, SERS spectra implied that small molecules bind on the outside of the DNA analogues, while exist mainly as free molecules in equimolar ratio with the synthetic RNA polynucleotide, thereby indicating higher affinity for DNA than for RNA.pl
dc.affiliationWydział Chemii : Zakład Chemii Organicznejpl
dc.contributor.authorMiljanić, Snežanapl
dc.contributor.authorDijanošić, Adrianapl
dc.contributor.authorKalac, Mateapl
dc.contributor.authorRadić Stojković, Marijanapl
dc.contributor.authorPiantanida, Ivopl
dc.contributor.authorPawlica, Dariuszpl
dc.contributor.authorEilmes, Julita - 127872 pl
dc.date.accession2019-01-22pl
dc.date.accessioned2015-09-15T07:55:44Z
dc.date.available2015-09-15T07:55:44Z
dc.date.issued2012pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalDariusz Pawlica - Instytut Chemii.pl
dc.description.number4pl
dc.description.physical577-584pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume85pl
dc.identifier.doi10.5562/cca2106pl
dc.identifier.eissn1334-417Xpl
dc.identifier.issn0011-1643pl
dc.identifier.projectROD UJ / Ppl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/15646
dc.identifier.weblinkhttps://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=139013pl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa*
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.ensurface-enhanced Raman scatteringpl
dc.subject.enpolynucleotidepl
dc.subject.enbindingpl
dc.subject.enannulenepl
dc.subtypeArticlepl
dc.titleSurface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotidespl
dc.title.journalCroatica Chemica Actapl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T22:09:45Z
dc.abstract.enpl
Binding modes of a dibenzotetraaza[14]annulene (DBTAA) derivative with synthetic nucleic acids were studied using surface-enhanced Raman spectroscopy (SERS). Changes in SERS intensity and appearance of new bands in spectra were attributed to different complexes formed between the DBTAA molecules and DNA/RNA polynucleotides. A decrease in intensity pointed to intercalation as the dominant binding mode of the annulene derivative with poly dGdC-poly dGdC and poly rA-poly rU, whereas new bands in the spectra at 735 cm−1 and 1345 cm−1 revealed binding within the minor groove of poly dAdT-poly dAdT. When all the dominant binding sites were occupied, SERS spectra implied that small molecules bind on the outside of the DNA analogues, while exist mainly as free molecules in equimolar ratio with the synthetic RNA polynucleotide, thereby indicating higher affinity for DNA than for RNA.
dc.affiliationpl
Wydział Chemii : Zakład Chemii Organicznej
dc.contributor.authorpl
Miljanić, Snežana
dc.contributor.authorpl
Dijanošić, Adriana
dc.contributor.authorpl
Kalac, Matea
dc.contributor.authorpl
Radić Stojković, Marijana
dc.contributor.authorpl
Piantanida, Ivo
dc.contributor.authorpl
Pawlica, Dariusz
dc.contributor.authorpl
Eilmes, Julita - 127872
dc.date.accessionpl
2019-01-22
dc.date.accessioned
2015-09-15T07:55:44Z
dc.date.available
2015-09-15T07:55:44Z
dc.date.issuedpl
2012
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Dariusz Pawlica - Instytut Chemii.
dc.description.numberpl
4
dc.description.physicalpl
577-584
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
85
dc.identifier.doipl
10.5562/cca2106
dc.identifier.eissnpl
1334-417X
dc.identifier.issnpl
0011-1643
dc.identifier.projectpl
ROD UJ / P
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/15646
dc.identifier.weblinkpl
https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=139013
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri*
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
surface-enhanced Raman scattering
dc.subject.enpl
polynucleotide
dc.subject.enpl
binding
dc.subject.enpl
annulene
dc.subtypepl
Article
dc.titlepl
Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides
dc.title.journalpl
Croatica Chemica Acta
dc.typepl
JournalArticle
dspace.entity.type
Publication

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