Microvascular density and mast cells in benign and malignant pheochromocytomas

2012
journal article
article
12
dc.abstract.enPheochromocytomas, uncommon adrenal tumors, have an uncertain behavior. Recently, PASS criteria were proposed for differentiating between benign and malignant cases. These are not perfect, however. The aim of the study was to investigate angiogenesis and mast cell density in context of the clinical behavior and morphologic characteristics of pheochromocytomas. Mean intratumoral chymase positive cell count was 14.50 for malignant, 15.73 for benign cases; mean subcapsular chymase positive cell count was 12.50 for malignant, 11.27 for benign cases.Mean intratumoral tryptase positive cell count was 17.50 for malignant and 17.91 for benign cases; mean subcapsular tryptase positive cell count was 15.25 for malignant and 15.73 for benign cases.Mean intratumoral CD31 positive vessel count was 46.98 for malignant and 51.02 for benign cases; mean subcapsular CD31 positive vessel count was 44.86 for malignant and 39.81 for benign cases. Mean intratumoral CD105 positive vessel count was 37.84 for malignant and 35.95 for benign cases; mean subcapsular CD105 positive vessel count was 26.36 for malignant and 22.03 for benign cases. The differences between benign and malignant cases were not significant. All the vascular counts were correlated with mast cells counts. PASS index was inversely correlated with mast cell counts.pl
dc.affiliationWydział Lekarski : Zakład Patomorfologii Klinicznej i Doświadczalnejpl
dc.contributor.authorUlatowska-Białas, Magdalena - 128741 pl
dc.contributor.authorDyduch, Grzegorz - 129300 pl
dc.contributor.authorSzpor, Joanna - 133600 pl
dc.contributor.authorDemczuk, Sergiusz - 129171 pl
dc.contributor.authorOkoń, Krzysztof - 133027 pl
dc.date.accession2020-04-28pl
dc.date.accessioned2020-04-28T09:59:24Z
dc.date.available2020-04-28T09:59:24Z
dc.date.issued2012pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 241-242. Na publikacji autorka Ulatowska-Białas Magdalena podpisana jako Białas Magdalena.pl
dc.description.number4pl
dc.description.physical235-242pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume63pl
dc.identifier.doi10.5114/pjp.2012.32770pl
dc.identifier.eissn2084-9869pl
dc.identifier.issn1233-9687pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/154753
dc.identifier.weblinkhttps://www.termedia.pl/Microvascular-density-and-mast-cells-in-benign-and-malignant-pheochromocytomas,55,20116,1,1.htmlpl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-SA
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enpheochromocytomapl
dc.subject.enmast cellspl
dc.subject.enangiogenesispl
dc.subject.enmicrovessels densitypl
dc.subtypeArticlepl
dc.titleMicrovascular density and mast cells in benign and malignant pheochromocytomaspl
dc.title.journalPolish Journal of Pathologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Pheochromocytomas, uncommon adrenal tumors, have an uncertain behavior. Recently, PASS criteria were proposed for differentiating between benign and malignant cases. These are not perfect, however. The aim of the study was to investigate angiogenesis and mast cell density in context of the clinical behavior and morphologic characteristics of pheochromocytomas. Mean intratumoral chymase positive cell count was 14.50 for malignant, 15.73 for benign cases; mean subcapsular chymase positive cell count was 12.50 for malignant, 11.27 for benign cases.Mean intratumoral tryptase positive cell count was 17.50 for malignant and 17.91 for benign cases; mean subcapsular tryptase positive cell count was 15.25 for malignant and 15.73 for benign cases.Mean intratumoral CD31 positive vessel count was 46.98 for malignant and 51.02 for benign cases; mean subcapsular CD31 positive vessel count was 44.86 for malignant and 39.81 for benign cases. Mean intratumoral CD105 positive vessel count was 37.84 for malignant and 35.95 for benign cases; mean subcapsular CD105 positive vessel count was 26.36 for malignant and 22.03 for benign cases. The differences between benign and malignant cases were not significant. All the vascular counts were correlated with mast cells counts. PASS index was inversely correlated with mast cell counts.
dc.affiliationpl
Wydział Lekarski : Zakład Patomorfologii Klinicznej i Doświadczalnej
dc.contributor.authorpl
Ulatowska-Białas, Magdalena - 128741
dc.contributor.authorpl
Dyduch, Grzegorz - 129300
dc.contributor.authorpl
Szpor, Joanna - 133600
dc.contributor.authorpl
Demczuk, Sergiusz - 129171
dc.contributor.authorpl
Okoń, Krzysztof - 133027
dc.date.accessionpl
2020-04-28
dc.date.accessioned
2020-04-28T09:59:24Z
dc.date.available
2020-04-28T09:59:24Z
dc.date.issuedpl
2012
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 241-242. Na publikacji autorka Ulatowska-Białas Magdalena podpisana jako Białas Magdalena.
dc.description.numberpl
4
dc.description.physicalpl
235-242
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
63
dc.identifier.doipl
10.5114/pjp.2012.32770
dc.identifier.eissnpl
2084-9869
dc.identifier.issnpl
1233-9687
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/154753
dc.identifier.weblinkpl
https://www.termedia.pl/Microvascular-density-and-mast-cells-in-benign-and-malignant-pheochromocytomas,55,20116,1,1.html
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-SA
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
pheochromocytoma
dc.subject.enpl
mast cells
dc.subject.enpl
angiogenesis
dc.subject.enpl
microvessels density
dc.subtypepl
Article
dc.titlepl
Microvascular density and mast cells in benign and malignant pheochromocytomas
dc.title.journalpl
Polish Journal of Pathology
dc.typepl
JournalArticle
dspace.entity.type
Publication

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