Giant schwannoma of the cheek : a comprehensive histological and immunohistochemical description of a rare tumour

2009
journal article
article
dc.abstract.enSchwannoma is a benign tumour originating from Schwann cells forming sheaths of peripheral nerves. Its location in the oral cavity, and particularly in the cheek, is very rare. A large tumour (5 cm) was surgically removed from the left cheek of a fifty-five-year-old man and pathological examination revealed schwannoma with Antoni A and B patterns. The tumour was investigated using immunofluorescence and histochemical stainings. It showed positive immunostaining for S-100, PGP 9.5, NSE, collagen IV, laminin, merosin and vimentin. No immunofluorescence for GFAP, NPY and CGRP was observed. Cells of the macrophage family (CD68-immunopositive) were scattered in the connective tissue. Neither B (CD20+) nor T (CD3+, CD8+) lymphocytes were found. The capillary network was revealed by CD34 immunostaining. SMA immunoreactivity was observed in walls of larger blood vessels but not in tumour cells. The tumour contained numerous mast cells visualized by thionin staining and an abundance of collagen fibres revealed by picrosirius red.pl
dc.affiliationWydział Lekarski : Zakład Histologiipl
dc.affiliationWydział Lekarski : Zakład Neuropatologiipl
dc.contributor.authorGajda, Mariusz - 129426 pl
dc.contributor.authorZagólski, Olafpl
dc.contributor.authorJasztal, Agnieszka - 129875 pl
dc.contributor.authorLis, Grzegorz - 130689 pl
dc.contributor.authorAdamek, Dariusz - 128411 pl
dc.contributor.authorLitwin, Jan - 130699 pl
dc.date.accession2020-04-23pl
dc.date.accessioned2020-04-23T19:59:08Z
dc.date.available2020-04-23T19:59:08Z
dc.date.issued2009pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 56.pl
dc.description.number1pl
dc.description.physical52-56pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume60pl
dc.identifier.eissn2084-9869pl
dc.identifier.issn1233-9687pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/154483
dc.identifier.weblinkhttps://www.termedia.pl/Giant-schwannoma-of-the-cheek-8211-a-comprehensive-histological-and-immunohistochemical-description-of-a-rare-tumour,55,12398,1,1.htmlpl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-SA
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subtypeArticlepl
dc.titleGiant schwannoma of the cheek : a comprehensive histological and immunohistochemical description of a rare tumourpl
dc.title.journalPolish Journal of Pathologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Schwannoma is a benign tumour originating from Schwann cells forming sheaths of peripheral nerves. Its location in the oral cavity, and particularly in the cheek, is very rare. A large tumour (5 cm) was surgically removed from the left cheek of a fifty-five-year-old man and pathological examination revealed schwannoma with Antoni A and B patterns. The tumour was investigated using immunofluorescence and histochemical stainings. It showed positive immunostaining for S-100, PGP 9.5, NSE, collagen IV, laminin, merosin and vimentin. No immunofluorescence for GFAP, NPY and CGRP was observed. Cells of the macrophage family (CD68-immunopositive) were scattered in the connective tissue. Neither B (CD20+) nor T (CD3+, CD8+) lymphocytes were found. The capillary network was revealed by CD34 immunostaining. SMA immunoreactivity was observed in walls of larger blood vessels but not in tumour cells. The tumour contained numerous mast cells visualized by thionin staining and an abundance of collagen fibres revealed by picrosirius red.
dc.affiliationpl
Wydział Lekarski : Zakład Histologii
dc.affiliationpl
Wydział Lekarski : Zakład Neuropatologii
dc.contributor.authorpl
Gajda, Mariusz - 129426
dc.contributor.authorpl
Zagólski, Olaf
dc.contributor.authorpl
Jasztal, Agnieszka - 129875
dc.contributor.authorpl
Lis, Grzegorz - 130689
dc.contributor.authorpl
Adamek, Dariusz - 128411
dc.contributor.authorpl
Litwin, Jan - 130699
dc.date.accessionpl
2020-04-23
dc.date.accessioned
2020-04-23T19:59:08Z
dc.date.available
2020-04-23T19:59:08Z
dc.date.issuedpl
2009
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 56.
dc.description.numberpl
1
dc.description.physicalpl
52-56
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
60
dc.identifier.eissnpl
2084-9869
dc.identifier.issnpl
1233-9687
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/154483
dc.identifier.weblinkpl
https://www.termedia.pl/Giant-schwannoma-of-the-cheek-8211-a-comprehensive-histological-and-immunohistochemical-description-of-a-rare-tumour,55,12398,1,1.html
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-SA
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subtypepl
Article
dc.titlepl
Giant schwannoma of the cheek : a comprehensive histological and immunohistochemical description of a rare tumour
dc.title.journalpl
Polish Journal of Pathology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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