Protein-protein interaction encoded as an exposure of hydrophobic residues on the surface

2020
book section
article
10
cris.lastimport.wos2024-04-09T21:06:37Z
dc.abstract.enAccording to the fuzzy oil drop model, information required for complexation of an external polypeptide chain should be encoded as a local exposure of hydrophobicity on the protein surface. Of course, this is not the sole mechanism by which protein complexes may emerge; however, exposed hydrophobicity appears to play an important part in the complexation process. A local excess of hydrophobicity – especially if occurring on the surface – creates an environment which favors interaction with other polypeptide chains; particularly those, which also expose a hydrophobic interface.pl
dc.affiliationWydział Lekarski : Zakład Bioinformatyki i Telemedycynypl
dc.cm.id97665
dc.contributor.authorBanach, Mateusz - 103003 pl
dc.contributor.authorKonieczny, Leszekpl
dc.contributor.authorRoterman-Konieczna, Irena - 133298 pl
dc.contributor.editorRoterman-Konieczna, Irena - 133298 pl
dc.date.accessioned2020-04-08T13:31:51Z
dc.date.available2020-04-08T13:31:51Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.physical79-89pl
dc.description.publication0,5pl
dc.description.versionostateczna wersja wydawcy
dc.identifier.doi10.1016/B978-0-08-102981-7.00008-7pl
dc.identifier.isbn978-0-08-102981-7pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/153493
dc.languageengpl
dc.language.containerengpl
dc.pubinfoAmsterdampl
dc.pubinfoOxfordpl
dc.pubinfoCambridge : Elsevierpl
dc.publisher.ministerialElsevierpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeinne
dc.sourceinfoliczba autorów 7; liczba stron 277; liczba arkuszy wydawniczych 16,35;pl
dc.subtypeArticlepl
dc.titleProtein-protein interaction encoded as an exposure of hydrophobic residues on the surfacepl
dc.title.containerFrom globular proteins to amyloidspl
dc.typeBookSectionpl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T21:06:37Z
dc.abstract.enpl
According to the fuzzy oil drop model, information required for complexation of an external polypeptide chain should be encoded as a local exposure of hydrophobicity on the protein surface. Of course, this is not the sole mechanism by which protein complexes may emerge; however, exposed hydrophobicity appears to play an important part in the complexation process. A local excess of hydrophobicity – especially if occurring on the surface – creates an environment which favors interaction with other polypeptide chains; particularly those, which also expose a hydrophobic interface.
dc.affiliationpl
Wydział Lekarski : Zakład Bioinformatyki i Telemedycyny
dc.cm.id
97665
dc.contributor.authorpl
Banach, Mateusz - 103003
dc.contributor.authorpl
Konieczny, Leszek
dc.contributor.authorpl
Roterman-Konieczna, Irena - 133298
dc.contributor.editorpl
Roterman-Konieczna, Irena - 133298
dc.date.accessioned
2020-04-08T13:31:51Z
dc.date.available
2020-04-08T13:31:51Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.physicalpl
79-89
dc.description.publicationpl
0,5
dc.description.version
ostateczna wersja wydawcy
dc.identifier.doipl
10.1016/B978-0-08-102981-7.00008-7
dc.identifier.isbnpl
978-0-08-102981-7
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/153493
dc.languagepl
eng
dc.language.containerpl
eng
dc.pubinfopl
Amsterdam
dc.pubinfopl
Oxford
dc.pubinfopl
Cambridge : Elsevier
dc.publisher.ministerialpl
Elsevier
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
inne
dc.sourceinfopl
liczba autorów 7; liczba stron 277; liczba arkuszy wydawniczych 16,35;
dc.subtypepl
Article
dc.titlepl
Protein-protein interaction encoded as an exposure of hydrophobic residues on the surface
dc.title.containerpl
From globular proteins to amyloids
dc.typepl
BookSection
dspace.entity.type
Publication
Affiliations

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