Kidney dysfunction after non renal solid organ transplantation

2009
journal article
article
dc.abstract.enChronic kidney disease developed after non renal solid organ transplantation in a significant issue. Evaluation of kidney function starting form a complete history and physical examination, then an accurate measurement of renal function and a urinalysis, followed by kidney imaging study should be performed prior to transplantation. Moreover, probability of reversibility of kidney dysfunction and the risk of progression to end stage renal disease should be assessed. During periand postoperative period hypotensive episodes should be avoided or at least minimized. Good blood pressure control (however, no guidelines for target blood pressure values for non solid organ transplants are available) as well as tight control of diabetes and hyperlipidemia should be implemented. Proteinuria, if present, should be attenuated by the use of therapeutic modalities (RAS blockade) to prevent or delay the progression of renal failure. The ability to identify CKD may allow early implementation of treatments that could arrest or delay the progression of renal damage, enable effective treatment of its complications, and reduce the risk of drug-induced nephrotoxicity. Kidney function should be monitored in nonrenal solid organ transplant recipients as an important risk factor comparable with diabetes for cardiovascular mortality and morbidity. In presence of existing nephron sparing immunosuppressive regimens, early detection of deteriorating kidney function gives the opportunity to tailor the treatment. A multidisciplinary approach for these patients including also a nephrologist should be considered.pl
dc.affiliationWydział Lekarski : Klinika Chirurgii Ogólnej, Onkologicznej i Gastroenterologicznejpl
dc.contributor.authorMalyszko, Jolantapl
dc.contributor.authorDurlik, Magdalenapl
dc.contributor.authorPrzybyłowski, Piotr - 133230 pl
dc.date.accession2020-04-03pl
dc.date.accessioned2020-04-03T13:21:05Z
dc.date.available2020-04-03T13:21:05Z
dc.date.issued2009pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 77-79pl
dc.description.number4pl
dc.description.physical71-79pl
dc.description.publication1pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume14pl
dc.identifier.eissn2329-0358pl
dc.identifier.issn1425-9524pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/153187
dc.identifier.weblinkhttp://www.annalsoftransplantation.com/fulltxt.php?ICID=900247pl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enchronic kidney diseasepl
dc.subject.enheart transplantationpl
dc.subject.enkidney transplantationpl
dc.subject.enliver transplantationpl
dc.subtypeArticlepl
dc.titleKidney dysfunction after non renal solid organ transplantationpl
dc.title.journalAnnals of Transplantationpl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Chronic kidney disease developed after non renal solid organ transplantation in a significant issue. Evaluation of kidney function starting form a complete history and physical examination, then an accurate measurement of renal function and a urinalysis, followed by kidney imaging study should be performed prior to transplantation. Moreover, probability of reversibility of kidney dysfunction and the risk of progression to end stage renal disease should be assessed. During periand postoperative period hypotensive episodes should be avoided or at least minimized. Good blood pressure control (however, no guidelines for target blood pressure values for non solid organ transplants are available) as well as tight control of diabetes and hyperlipidemia should be implemented. Proteinuria, if present, should be attenuated by the use of therapeutic modalities (RAS blockade) to prevent or delay the progression of renal failure. The ability to identify CKD may allow early implementation of treatments that could arrest or delay the progression of renal damage, enable effective treatment of its complications, and reduce the risk of drug-induced nephrotoxicity. Kidney function should be monitored in nonrenal solid organ transplant recipients as an important risk factor comparable with diabetes for cardiovascular mortality and morbidity. In presence of existing nephron sparing immunosuppressive regimens, early detection of deteriorating kidney function gives the opportunity to tailor the treatment. A multidisciplinary approach for these patients including also a nephrologist should be considered.
dc.affiliationpl
Wydział Lekarski : Klinika Chirurgii Ogólnej, Onkologicznej i Gastroenterologicznej
dc.contributor.authorpl
Malyszko, Jolanta
dc.contributor.authorpl
Durlik, Magdalena
dc.contributor.authorpl
Przybyłowski, Piotr - 133230
dc.date.accessionpl
2020-04-03
dc.date.accessioned
2020-04-03T13:21:05Z
dc.date.available
2020-04-03T13:21:05Z
dc.date.issuedpl
2009
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 77-79
dc.description.numberpl
4
dc.description.physicalpl
71-79
dc.description.publicationpl
1
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
14
dc.identifier.eissnpl
2329-0358
dc.identifier.issnpl
1425-9524
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/153187
dc.identifier.weblinkpl
http://www.annalsoftransplantation.com/fulltxt.php?ICID=900247
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
chronic kidney disease
dc.subject.enpl
heart transplantation
dc.subject.enpl
kidney transplantation
dc.subject.enpl
liver transplantation
dc.subtypepl
Article
dc.titlepl
Kidney dysfunction after non renal solid organ transplantation
dc.title.journalpl
Annals of Transplantation
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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