Effect of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis

2018
journal article
article
cris.lastimport.wos2024-04-09T23:29:15Z
dc.abstract.enBackground: Diabetes mellitus (DM) is considered a marker of poor prognosis after cardiac surgery. We sought to investigate the effect of DM on clinical outcomes and quality of life (QoL) after transcatheter aortic valve implantation (TAVI). Methods: A total of 148 consecutive patients with symptomatic, severe aortic stenosis who underwent TAVI were included. Baseline characteristics, procedural and long-term clinical outcomes, and the results of frailty and QoL assessment with EQ-5D-3L questionnaire were compared between patients with and without DM. Results: DM was present in 48 of 148 (32.4%) patients. No differences in periprocedural risk (Logistic Euroscore and Society of Thoracic Surgeons (STS) scale) between groups were observed. There were no differences in 30-day and 12-month all-cause mortality between groups [DM( ) vs. DM(þ): 7 (7.0%) vs. 5 (10.4%), p Z 0.53 and 12 (12.0%) vs. 10 (20.8%), p Z 0.16, respectively]. No influence of DM presence on the risk of death was confirmed after adjustment for age and gender (for 30-day mortality, age/gender-adjusted OR 1.55, 95%CI 0.47 e5.17; for 12-month mortality, age/gender-adjusted OR 2.05, 95%CI 0.79e5.32). Similarly, at the longest available follow-up, mortality did not differ between groups [14 (29.2%) vs. 19 (19.0%), p Z 0.16; age/gender-adjusted OR 1.81, 95%CI 0.80e4.08]. Similar rates of other complications after TAVI were noted. Frailty measured with the 5-meter walking test was more frequently reported in patients with DM [11 (22.9%) vs. 10 (10.0%), p Z 0.035]. No differences in QoL parameters at baseline and 12 months were noted. Conclusions: Patients with DM undergoing TAVI demonstrated similar mortality, complication rates, and QoL outcomes compared to patients without DMpl
dc.affiliationWydział Lekarski : Instytut Kardiologiipl
dc.cm.date2020-01-07
dc.cm.id84836
dc.contributor.authorTokarek, Tomasz - 162633 pl
dc.contributor.authorDziewierz, Artur - 241962 pl
dc.contributor.authorWiktorowicz, Agatapl
dc.contributor.authorBagienski, Maciejpl
dc.contributor.authorRzeszutko, Łukaszpl
dc.contributor.authorSorysz, Danutapl
dc.contributor.authorKleczyński, Paweł - 148282 pl
dc.contributor.authorDudek, Dariusz - 129271 pl
dc.date.accessioned2020-01-17T09:17:49Z
dc.date.available2020-01-17T09:17:49Z
dc.date.issued2018pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number2pl
dc.description.physical100-107pl
dc.description.points20pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume59pl
dc.identifier.doi10.1016/j.hjc.2017.08.002pl
dc.identifier.eissn2241-5955pl
dc.identifier.issn1109-9666pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/141274
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeinne
dc.subject.enfrailtypl
dc.subject.entranscatheter aortic valve replacementpl
dc.subject.enaortic valve diseasepl
dc.subject.enhigh-risk patientspl
dc.subject.enregistrypl
dc.subtypeArticlepl
dc.titleEffect of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosispl
dc.title.journalHellenic Journal of Cardiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T23:29:15Z
dc.abstract.enpl
Background: Diabetes mellitus (DM) is considered a marker of poor prognosis after cardiac surgery. We sought to investigate the effect of DM on clinical outcomes and quality of life (QoL) after transcatheter aortic valve implantation (TAVI). Methods: A total of 148 consecutive patients with symptomatic, severe aortic stenosis who underwent TAVI were included. Baseline characteristics, procedural and long-term clinical outcomes, and the results of frailty and QoL assessment with EQ-5D-3L questionnaire were compared between patients with and without DM. Results: DM was present in 48 of 148 (32.4%) patients. No differences in periprocedural risk (Logistic Euroscore and Society of Thoracic Surgeons (STS) scale) between groups were observed. There were no differences in 30-day and 12-month all-cause mortality between groups [DM( ) vs. DM(þ): 7 (7.0%) vs. 5 (10.4%), p Z 0.53 and 12 (12.0%) vs. 10 (20.8%), p Z 0.16, respectively]. No influence of DM presence on the risk of death was confirmed after adjustment for age and gender (for 30-day mortality, age/gender-adjusted OR 1.55, 95%CI 0.47 e5.17; for 12-month mortality, age/gender-adjusted OR 2.05, 95%CI 0.79e5.32). Similarly, at the longest available follow-up, mortality did not differ between groups [14 (29.2%) vs. 19 (19.0%), p Z 0.16; age/gender-adjusted OR 1.81, 95%CI 0.80e4.08]. Similar rates of other complications after TAVI were noted. Frailty measured with the 5-meter walking test was more frequently reported in patients with DM [11 (22.9%) vs. 10 (10.0%), p Z 0.035]. No differences in QoL parameters at baseline and 12 months were noted. Conclusions: Patients with DM undergoing TAVI demonstrated similar mortality, complication rates, and QoL outcomes compared to patients without DM
dc.affiliationpl
Wydział Lekarski : Instytut Kardiologii
dc.cm.date
2020-01-07
dc.cm.id
84836
dc.contributor.authorpl
Tokarek, Tomasz - 162633
dc.contributor.authorpl
Dziewierz, Artur - 241962
dc.contributor.authorpl
Wiktorowicz, Agata
dc.contributor.authorpl
Bagienski, Maciej
dc.contributor.authorpl
Rzeszutko, Łukasz
dc.contributor.authorpl
Sorysz, Danuta
dc.contributor.authorpl
Kleczyński, Paweł - 148282
dc.contributor.authorpl
Dudek, Dariusz - 129271
dc.date.accessioned
2020-01-17T09:17:49Z
dc.date.available
2020-01-17T09:17:49Z
dc.date.issuedpl
2018
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
2
dc.description.physicalpl
100-107
dc.description.pointspl
20
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
59
dc.identifier.doipl
10.1016/j.hjc.2017.08.002
dc.identifier.eissnpl
2241-5955
dc.identifier.issnpl
1109-9666
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/141274
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
inne
dc.subject.enpl
frailty
dc.subject.enpl
transcatheter aortic valve replacement
dc.subject.enpl
aortic valve disease
dc.subject.enpl
high-risk patients
dc.subject.enpl
registry
dc.subtypepl
Article
dc.titlepl
Effect of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis
dc.title.journalpl
Hellenic Journal of Cardiology
dc.typepl
JournalArticle
dspace.entity.type
Publication

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