Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland

2017
journal article
article
9
dc.abstract.enIntroduction: Ulcerative colitis (UC) require expensive, lifelong treatment, which generates huge direct costs and has a significant impact on the quality of life, especially in the active state of the disease. Aim: To assess the indirect costs, health-related quality of life, and clinical characteristics of patients with UC in Poland. Additionally, we investigated the association between activity of UC and productivity loss of patients in a Polish setting. Material and methods: A questionnaire survey was conducted using the Patient Simple Clinical Colitis Activity Index (P-SCCAI) to assess disease activity, as well as the modified Work Productivity and Activity Impairment Questionnaire to assess productivity loss. The quality of life was presented as utility calculated with the EQ-5D-3L questionnaire. Indirect costs were assessed with the Human Capital Approach and were expressed in Polish zlotys (PLN) as well as in euros (€). Correlations were presented using the Spearman coefficient. Results: We performed our analysis based on 202 full questionnaires collected. Mean patient age and age at disease onset were 33.14 years (standard deviation (SD): 9.90) and 26.35 years (SD: 8.89), respectively. The mean P-SCCAI score in the analysed group of patients was 8.26, and the mean utility was 0.8651. Average and median annual indirect costs per working person were €2043 and €1389 (8543 PLN and 5808 PLN), respectively, calculated using the gross domestic product, as well as €4791 and €3257 (20,026 PLN and 13,615 PLN), respectively, calculated using the gross value added. Total productivity loss was significantly correlated with the disease activity. Conclusions: Ulcerative colitis causes a decrease in the quality of life as well as patients’ productivity loss associated with both absenteeism and with presenteeism.pl
dc.affiliationWydział Nauk o Zdrowiu : Instytut Zdrowia Publicznegopl
dc.cm.date2020-01-07
dc.cm.id81793
dc.contributor.authorKawalec, Paweł - 130055 pl
dc.contributor.authorStawowczyk, Ewapl
dc.contributor.authorMossakowska, Małgorzatapl
dc.contributor.authorPilc, Andrzej - 133153 pl
dc.date.accessioned2020-01-17T09:15:32Z
dc.date.available2020-01-17T09:15:32Z
dc.date.issued2017pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number1pl
dc.description.physical60-65pl
dc.description.points15pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume12pl
dc.identifier.doi10.5114/pg.2017.66324pl
dc.identifier.eissn1897-4317
dc.identifier.issn1895-5770pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/140348
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-SA
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enulcerative colitispl
dc.subject.enquality of lifepl
dc.subject.enindirect costspl
dc.subject.enproductivity losspl
dc.subtypeArticlepl
dc.titleDisease activity, quality of life, and indirect costs of ulcerative colitis in Polandpl
dc.title.journalPrzegląd Gastroenterologicznypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Introduction: Ulcerative colitis (UC) require expensive, lifelong treatment, which generates huge direct costs and has a significant impact on the quality of life, especially in the active state of the disease. Aim: To assess the indirect costs, health-related quality of life, and clinical characteristics of patients with UC in Poland. Additionally, we investigated the association between activity of UC and productivity loss of patients in a Polish setting. Material and methods: A questionnaire survey was conducted using the Patient Simple Clinical Colitis Activity Index (P-SCCAI) to assess disease activity, as well as the modified Work Productivity and Activity Impairment Questionnaire to assess productivity loss. The quality of life was presented as utility calculated with the EQ-5D-3L questionnaire. Indirect costs were assessed with the Human Capital Approach and were expressed in Polish zlotys (PLN) as well as in euros (€). Correlations were presented using the Spearman coefficient. Results: We performed our analysis based on 202 full questionnaires collected. Mean patient age and age at disease onset were 33.14 years (standard deviation (SD): 9.90) and 26.35 years (SD: 8.89), respectively. The mean P-SCCAI score in the analysed group of patients was 8.26, and the mean utility was 0.8651. Average and median annual indirect costs per working person were €2043 and €1389 (8543 PLN and 5808 PLN), respectively, calculated using the gross domestic product, as well as €4791 and €3257 (20,026 PLN and 13,615 PLN), respectively, calculated using the gross value added. Total productivity loss was significantly correlated with the disease activity. Conclusions: Ulcerative colitis causes a decrease in the quality of life as well as patients’ productivity loss associated with both absenteeism and with presenteeism.
dc.affiliationpl
Wydział Nauk o Zdrowiu : Instytut Zdrowia Publicznego
dc.cm.date
2020-01-07
dc.cm.id
81793
dc.contributor.authorpl
Kawalec, Paweł - 130055
dc.contributor.authorpl
Stawowczyk, Ewa
dc.contributor.authorpl
Mossakowska, Małgorzata
dc.contributor.authorpl
Pilc, Andrzej - 133153
dc.date.accessioned
2020-01-17T09:15:32Z
dc.date.available
2020-01-17T09:15:32Z
dc.date.issuedpl
2017
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
1
dc.description.physicalpl
60-65
dc.description.pointspl
15
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
12
dc.identifier.doipl
10.5114/pg.2017.66324
dc.identifier.eissn
1897-4317
dc.identifier.issnpl
1895-5770
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/140348
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-SA
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
ulcerative colitis
dc.subject.enpl
quality of life
dc.subject.enpl
indirect costs
dc.subject.enpl
productivity loss
dc.subtypepl
Article
dc.titlepl
Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland
dc.title.journalpl
Przegląd Gastroenterologiczny
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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