Palisaded neutrophilic and granulomatous dermatitis : cutaneous manifestation of Lyme disease or connected with CTD? Case report

2016
journal article
article
3
cris.lastimport.wos2024-04-09T20:47:14Z
dc.abstract.enIntroduction. Palisaded neutrophilic and granulomatous dermatitis (PNGD) are terms which include such diseases as rheumatoid nodules, Churg-Strauss granuloma, and interstitial granulomatous dermatitis with arthritis. This heterogeneous group was first described in 1965. It is associated with immunological diseases. There are reported cases of coexistence with systemic lupus erythematosus, rheumatoid arthritis, Wegener‘s granuloma, inflammatory bowel disease, generalized vascular inflammation, and lymphoproliferative disorders. The etiology of the disease is unknown. It is probable that the deposition of immune complexes in blood vessels leads to cutaneus leukocytoclastic vasculitis, degeneration of collagen fibres and palisaded granulomatous inflammation. Ultimately, this leads to fibrosis of the skin. Objective. The aim of the study is to present a patient with skin lesions and histopathological features of palisaded neutrophilic and granulomatous dermatitis during the course of infection Borrelia burgdorferi. Several cases of this disease have been reported worldwide (30 entries in the PubMed database). To-date, there have been no reports of PNGD in Polish literature. Materials and method. The patient, aged 72, was admitted to hospital because of erythematous, indurated lesion of the skin on the side surface of the left thigh. Diagnosis of PNGD was made on the basis of typical histopathologic features due to clinical symptoms. Conclusions. Clinical diagnosis of PNGD is difficult, and is based mainly on the histopathological picture. Systemic therapy is incorporated mainly due to the systemic disease. The patient requires further observation in the direction of associated systemic disorders.pl
dc.affiliationWydział Lekarski : Klinika Dermatologiipl
dc.affiliationWydział Lekarski : Zakład Patomorfologii Klinicznej i Doświadczalnejpl
dc.cm.date2020-01-07
dc.cm.id78252
dc.contributor.authorPirowska, Magdalena - 140916 pl
dc.contributor.authorObtułowicz, Aleksander - 133017 pl
dc.contributor.authorDyduch, Grzegorz - 129300 pl
dc.contributor.authorLipko-Godlewska, Sylwia - 130682 pl
dc.contributor.authorWojas-Pelc, Anna - 133808 pl
dc.date.accessioned2020-01-17T09:09:04Z
dc.date.available2020-01-17T09:09:04Z
dc.date.issued2016pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number2pl
dc.description.physical384-386pl
dc.description.points20pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume23pl
dc.identifier.doi10.5604/12321966.1203913pl
dc.identifier.eissn1898-2263
dc.identifier.issn1232-1966pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/138156
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne 3.0 Polska*
dc.rights.licenceCC-BY-NC
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/pl/legalcode*
dc.share.typeotwarte czasopismo
dc.subject.enpalisaded neutrophilic and granulomatous dermatitispl
dc.subject.enborreliosis (Lyme disease)pl
dc.subject.enlupus erythematosuspl
dc.subtypeArticlepl
dc.titlePalisaded neutrophilic and granulomatous dermatitis : cutaneous manifestation of Lyme disease or connected with CTD? Case reportpl
dc.title.journalAnnals of Agricultural and Environmental Medicinepl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T20:47:14Z
dc.abstract.enpl
Introduction. Palisaded neutrophilic and granulomatous dermatitis (PNGD) are terms which include such diseases as rheumatoid nodules, Churg-Strauss granuloma, and interstitial granulomatous dermatitis with arthritis. This heterogeneous group was first described in 1965. It is associated with immunological diseases. There are reported cases of coexistence with systemic lupus erythematosus, rheumatoid arthritis, Wegener‘s granuloma, inflammatory bowel disease, generalized vascular inflammation, and lymphoproliferative disorders. The etiology of the disease is unknown. It is probable that the deposition of immune complexes in blood vessels leads to cutaneus leukocytoclastic vasculitis, degeneration of collagen fibres and palisaded granulomatous inflammation. Ultimately, this leads to fibrosis of the skin. Objective. The aim of the study is to present a patient with skin lesions and histopathological features of palisaded neutrophilic and granulomatous dermatitis during the course of infection Borrelia burgdorferi. Several cases of this disease have been reported worldwide (30 entries in the PubMed database). To-date, there have been no reports of PNGD in Polish literature. Materials and method. The patient, aged 72, was admitted to hospital because of erythematous, indurated lesion of the skin on the side surface of the left thigh. Diagnosis of PNGD was made on the basis of typical histopathologic features due to clinical symptoms. Conclusions. Clinical diagnosis of PNGD is difficult, and is based mainly on the histopathological picture. Systemic therapy is incorporated mainly due to the systemic disease. The patient requires further observation in the direction of associated systemic disorders.
dc.affiliationpl
Wydział Lekarski : Klinika Dermatologii
dc.affiliationpl
Wydział Lekarski : Zakład Patomorfologii Klinicznej i Doświadczalnej
dc.cm.date
2020-01-07
dc.cm.id
78252
dc.contributor.authorpl
Pirowska, Magdalena - 140916
dc.contributor.authorpl
Obtułowicz, Aleksander - 133017
dc.contributor.authorpl
Dyduch, Grzegorz - 129300
dc.contributor.authorpl
Lipko-Godlewska, Sylwia - 130682
dc.contributor.authorpl
Wojas-Pelc, Anna - 133808
dc.date.accessioned
2020-01-17T09:09:04Z
dc.date.available
2020-01-17T09:09:04Z
dc.date.issuedpl
2016
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
2
dc.description.physicalpl
384-386
dc.description.pointspl
20
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
23
dc.identifier.doipl
10.5604/12321966.1203913
dc.identifier.eissn
1898-2263
dc.identifier.issnpl
1232-1966
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/138156
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne 3.0 Polska
dc.rights.licence
CC-BY-NC
dc.rights.uri*
http://creativecommons.org/licenses/by-nc/3.0/pl/legalcode
dc.share.type
otwarte czasopismo
dc.subject.enpl
palisaded neutrophilic and granulomatous dermatitis
dc.subject.enpl
borreliosis (Lyme disease)
dc.subject.enpl
lupus erythematosus
dc.subtypepl
Article
dc.titlepl
Palisaded neutrophilic and granulomatous dermatitis : cutaneous manifestation of Lyme disease or connected with CTD? Case report
dc.title.journalpl
Annals of Agricultural and Environmental Medicine
dc.typepl
JournalArticle
dspace.entity.type
Publication

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