Thermographic assessment of skin prick tests in comparison with the routine evaluation methods

2016
journal article
article
6
cris.lastimport.wos2024-04-10T00:01:29Z
dc.abstract.enIntroduction: The skin prick test is still the first and basic procedure in the diagnosis of allergic diseases. The possibility of using a sensitive thermographic method supported by the mathematical model for the assessment of skin test results will be highlighted in the studies. Aim: To compare the proposed approach with routine planimetric and thermographic methods. Material and methods: A mathematical model of allergic reaction was developed. Simplifying assumptions of the IgE-mediated skin reaction is the essence of the model. Investigations were performed in a group of 40 patients. Results: Using the spatio-temporal evolution of temperature distributions, the ratios of the histamine released from mast cells to the control histamine were determined. The obtained values very well correlate with the standard evaluation of skin prick tests (correlation coefficient = 0.98). Conclusions: The proposed method of skin test evaluation presents several advantages. The continuous acquisition of data provides the monitoring of time course of the allergic response. The transport of mediator and its concentration were distinctly discriminated, which may be diagnostically useful, especially for abnormal cases. The high sensitivity of the method enables studying patients regardless of age and skin sensitivity.pl
dc.affiliationWydział Lekarski : Zakład Biofizykipl
dc.affiliationWydział Lekarski : Klinika Chorób Wewnętrznych i Medycyny Wsipl
dc.cm.date2020-01-07
dc.cm.id78182
dc.contributor.authorRok, Tomasz - 133290 pl
dc.contributor.authorRokita, Eugeniusz - 133291 pl
dc.contributor.authorTatoń, Grzegorz - 133654 pl
dc.contributor.authorGuzik, Tomasz - 129671 pl
dc.contributor.authorŚliwa, Tomasz - 133629 pl
dc.date.accessioned2020-01-17T09:09:02Z
dc.date.available2020-01-17T09:09:02Z
dc.date.issued2016pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number3pl
dc.description.physical193-198pl
dc.description.points15pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume33pl
dc.identifier.doi10.5114/ada.2016.60611pl
dc.identifier.eissn2299-0046pl
dc.identifier.issn1642-395Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/138112
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-SA
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enskin prick testspl
dc.subject.enthermographypl
dc.subject.enmathematical modelpl
dc.subtypeArticlepl
dc.titleThermographic assessment of skin prick tests in comparison with the routine evaluation methodspl
dc.title.journalPostępy Dermatologii i Alergologiipl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-10T00:01:29Z
dc.abstract.enpl
Introduction: The skin prick test is still the first and basic procedure in the diagnosis of allergic diseases. The possibility of using a sensitive thermographic method supported by the mathematical model for the assessment of skin test results will be highlighted in the studies. Aim: To compare the proposed approach with routine planimetric and thermographic methods. Material and methods: A mathematical model of allergic reaction was developed. Simplifying assumptions of the IgE-mediated skin reaction is the essence of the model. Investigations were performed in a group of 40 patients. Results: Using the spatio-temporal evolution of temperature distributions, the ratios of the histamine released from mast cells to the control histamine were determined. The obtained values very well correlate with the standard evaluation of skin prick tests (correlation coefficient = 0.98). Conclusions: The proposed method of skin test evaluation presents several advantages. The continuous acquisition of data provides the monitoring of time course of the allergic response. The transport of mediator and its concentration were distinctly discriminated, which may be diagnostically useful, especially for abnormal cases. The high sensitivity of the method enables studying patients regardless of age and skin sensitivity.
dc.affiliationpl
Wydział Lekarski : Zakład Biofizyki
dc.affiliationpl
Wydział Lekarski : Klinika Chorób Wewnętrznych i Medycyny Wsi
dc.cm.date
2020-01-07
dc.cm.id
78182
dc.contributor.authorpl
Rok, Tomasz - 133290
dc.contributor.authorpl
Rokita, Eugeniusz - 133291
dc.contributor.authorpl
Tatoń, Grzegorz - 133654
dc.contributor.authorpl
Guzik, Tomasz - 129671
dc.contributor.authorpl
Śliwa, Tomasz - 133629
dc.date.accessioned
2020-01-17T09:09:02Z
dc.date.available
2020-01-17T09:09:02Z
dc.date.issuedpl
2016
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
3
dc.description.physicalpl
193-198
dc.description.pointspl
15
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
33
dc.identifier.doipl
10.5114/ada.2016.60611
dc.identifier.eissnpl
2299-0046
dc.identifier.issnpl
1642-395X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/138112
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-SA
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
skin prick tests
dc.subject.enpl
thermography
dc.subject.enpl
mathematical model
dc.subtypepl
Article
dc.titlepl
Thermographic assessment of skin prick tests in comparison with the routine evaluation methods
dc.title.journalpl
Postępy Dermatologii i Alergologii
dc.typepl
JournalArticle
dspace.entity.type
Publication

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