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Influence of applied potential on bradykinin adsorption onto Ag, Au, and Cu electrodes
Na publikacji autorka Święch Dominika podpisana jako Skołuba Dominika.
Surface-enhanced Raman scattering, electrochemistry, and generalized two-dimensional correlation analysis (G2DCA) methods were used to characterize bradykinin (BK), a hormone which is known to be involved in small-cell and non-small-cell lung carcinoma and prostate cancer. BK was deposited onto Ag, Au, and Cu electrode surfaces under different applied electrode potentials (
1.000V to 0.200V) in aqueous solutions. Based on the analysis of the enhancement, the broadening, and the shifts in the wavenumbers of individual bands, speci fi c conclusions were drawn regarding the peptide geometry and changes in this geometry that occurred when the electrode type and applied electrode potential were varied. Brie fl y, BK deposited onto the Ag, Au, and Cu electrode surfaces showed bands that were due to the vibrations of moieties in contact with or in close proximity to the electrode surfaces and were thus located on the same side of the polypeptide backbone. These moieties included the Phe, Arg, and Pro residues. The fi ndingsfor adsorbed BKwere fully supportedbyG2DCA,which also allowed ustodeterminethe order in which changes occurred when the electrode potential was changed. In addition, it was found that at negative electrode potentials, the Phe rings and methylene groups interact with Ag electrode surface. No such interaction was observed for Au and Cu electrodes.
cris.lastimport.wos | 2024-04-10T00:22:43Z | |
dc.abstract.en | Surface-enhanced Raman scattering, electrochemistry, and generalized two-dimensional correlation analysis (G2DCA) methods were used to characterize bradykinin (BK), a hormone which is known to be involved in small-cell and non-small-cell lung carcinoma and prostate cancer. BK was deposited onto Ag, Au, and Cu electrode surfaces under different applied electrode potentials ( 1.000V to 0.200V) in aqueous solutions. Based on the analysis of the enhancement, the broadening, and the shifts in the wavenumbers of individual bands, speci fi c conclusions were drawn regarding the peptide geometry and changes in this geometry that occurred when the electrode type and applied electrode potential were varied. Brie fl y, BK deposited onto the Ag, Au, and Cu electrode surfaces showed bands that were due to the vibrations of moieties in contact with or in close proximity to the electrode surfaces and were thus located on the same side of the polypeptide backbone. These moieties included the Phe, Arg, and Pro residues. The fi ndingsfor adsorbed BKwere fully supportedbyG2DCA,which also allowed ustodeterminethe order in which changes occurred when the electrode potential was changed. In addition, it was found that at negative electrode potentials, the Phe rings and methylene groups interact with Ag electrode surface. No such interaction was observed for Au and Cu electrodes. | pl |
dc.affiliation | Wydział Chemii : Zakład Fizyki Chemicznej | pl |
dc.contributor.author | Proniewicz, Edyta - 131481 | pl |
dc.contributor.author | Święch, Dominika - 107027 | pl |
dc.contributor.author | Ignatjev, Ilja | pl |
dc.contributor.author | Niaura, Gediminas | pl |
dc.contributor.author | Sobolewski, Dariusz | pl |
dc.contributor.author | Prahl, Adam | pl |
dc.contributor.author | Proniewicz, Leonard - 131552 | pl |
dc.date.accessioned | 2015-06-22T13:35:58Z | |
dc.date.available | 2015-06-22T13:35:58Z | |
dc.date.issued | 2013 | pl |
dc.description.additional | Na publikacji autorka Święch Dominika podpisana jako Skołuba Dominika. | pl |
dc.description.admin | [AB] Proniewicz, Edyta [SAP11017634] 50000141 | pl |
dc.description.number | 5 | pl |
dc.description.physical | 655-664 | pl |
dc.description.volume | 44 | pl |
dc.identifier.doi | 10.1002/jrs.4246 | pl |
dc.identifier.eissn | 1097-4555 | pl |
dc.identifier.issn | 0377-0486 | pl |
dc.identifier.uri | http://ruj.uj.edu.pl/xmlui/handle/item/9989 | |
dc.language | eng | pl |
dc.language.container | eng | pl |
dc.rights.licence | bez licencji | |
dc.subtype | Article | pl |
dc.title | Influence of applied potential on bradykinin adsorption onto Ag, Au, and Cu electrodes | pl |
dc.title.journal | Journal of Raman Spectroscopy | pl |
dc.type | JournalArticle | pl |
dspace.entity.type | Publication |