Influence of applied potential on bradykinin adsorption onto Ag, Au, and Cu electrodes

2013
journal article
article
12
cris.lastimport.wos2024-04-10T00:22:43Z
dc.abstract.enSurface-enhanced Raman scattering, electrochemistry, and generalized two-dimensional correlation analysis (G2DCA) methods were used to characterize bradykinin (BK), a hormone which is known to be involved in small-cell and non-small-cell lung carcinoma and prostate cancer. BK was deposited onto Ag, Au, and Cu electrode surfaces under different applied electrode potentials ( 1.000V to 0.200V) in aqueous solutions. Based on the analysis of the enhancement, the broadening, and the shifts in the wavenumbers of individual bands, speci fi c conclusions were drawn regarding the peptide geometry and changes in this geometry that occurred when the electrode type and applied electrode potential were varied. Brie fl y, BK deposited onto the Ag, Au, and Cu electrode surfaces showed bands that were due to the vibrations of moieties in contact with or in close proximity to the electrode surfaces and were thus located on the same side of the polypeptide backbone. These moieties included the Phe, Arg, and Pro residues. The fi ndingsfor adsorbed BKwere fully supportedbyG2DCA,which also allowed ustodeterminethe order in which changes occurred when the electrode potential was changed. In addition, it was found that at negative electrode potentials, the Phe rings and methylene groups interact with Ag electrode surface. No such interaction was observed for Au and Cu electrodes.pl
dc.affiliationWydział Chemii : Zakład Fizyki Chemicznejpl
dc.contributor.authorProniewicz, Edyta - 131481 pl
dc.contributor.authorŚwięch, Dominika - 107027 pl
dc.contributor.authorIgnatjev, Iljapl
dc.contributor.authorNiaura, Gediminaspl
dc.contributor.authorSobolewski, Dariuszpl
dc.contributor.authorPrahl, Adampl
dc.contributor.authorProniewicz, Leonard - 131552 pl
dc.date.accessioned2015-06-22T13:35:58Z
dc.date.available2015-06-22T13:35:58Z
dc.date.issued2013pl
dc.description.additionalNa publikacji autorka Święch Dominika podpisana jako Skołuba Dominika.pl
dc.description.admin[AB] Proniewicz, Edyta [SAP11017634] 50000141pl
dc.description.number5pl
dc.description.physical655-664pl
dc.description.volume44pl
dc.identifier.doi10.1002/jrs.4246pl
dc.identifier.eissn1097-4555pl
dc.identifier.issn0377-0486pl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/9989
dc.languageengpl
dc.language.containerengpl
dc.rights.licencebez licencji
dc.subtypeArticlepl
dc.titleInfluence of applied potential on bradykinin adsorption onto Ag, Au, and Cu electrodespl
dc.title.journalJournal of Raman Spectroscopypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-10T00:22:43Z
dc.abstract.enpl
Surface-enhanced Raman scattering, electrochemistry, and generalized two-dimensional correlation analysis (G2DCA) methods were used to characterize bradykinin (BK), a hormone which is known to be involved in small-cell and non-small-cell lung carcinoma and prostate cancer. BK was deposited onto Ag, Au, and Cu electrode surfaces under different applied electrode potentials ( 1.000V to 0.200V) in aqueous solutions. Based on the analysis of the enhancement, the broadening, and the shifts in the wavenumbers of individual bands, speci fi c conclusions were drawn regarding the peptide geometry and changes in this geometry that occurred when the electrode type and applied electrode potential were varied. Brie fl y, BK deposited onto the Ag, Au, and Cu electrode surfaces showed bands that were due to the vibrations of moieties in contact with or in close proximity to the electrode surfaces and were thus located on the same side of the polypeptide backbone. These moieties included the Phe, Arg, and Pro residues. The fi ndingsfor adsorbed BKwere fully supportedbyG2DCA,which also allowed ustodeterminethe order in which changes occurred when the electrode potential was changed. In addition, it was found that at negative electrode potentials, the Phe rings and methylene groups interact with Ag electrode surface. No such interaction was observed for Au and Cu electrodes.
dc.affiliationpl
Wydział Chemii : Zakład Fizyki Chemicznej
dc.contributor.authorpl
Proniewicz, Edyta - 131481
dc.contributor.authorpl
Święch, Dominika - 107027
dc.contributor.authorpl
Ignatjev, Ilja
dc.contributor.authorpl
Niaura, Gediminas
dc.contributor.authorpl
Sobolewski, Dariusz
dc.contributor.authorpl
Prahl, Adam
dc.contributor.authorpl
Proniewicz, Leonard - 131552
dc.date.accessioned
2015-06-22T13:35:58Z
dc.date.available
2015-06-22T13:35:58Z
dc.date.issuedpl
2013
dc.description.additionalpl
Na publikacji autorka Święch Dominika podpisana jako Skołuba Dominika.
dc.description.adminpl
[AB] Proniewicz, Edyta [SAP11017634] 50000141
dc.description.numberpl
5
dc.description.physicalpl
655-664
dc.description.volumepl
44
dc.identifier.doipl
10.1002/jrs.4246
dc.identifier.eissnpl
1097-4555
dc.identifier.issnpl
0377-0486
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/9989
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights.licence
bez licencji
dc.subtypepl
Article
dc.titlepl
Influence of applied potential on bradykinin adsorption onto Ag, Au, and Cu electrodes
dc.title.journalpl
Journal of Raman Spectroscopy
dc.typepl
JournalArticle
dspace.entity.type
Publication

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