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Impact of vanadium complexes treatment on the oxidative stress factors in Wistar rats plasma
Journal
Bioinorganic Chemistry and Applications
Author
Volume
2011
Article ID
206316
ISSN
1565-3633
eISSN
1687-479X
Access date
2019-03-27
Remarks
Bibliogr. 206316-7 - 206316-8.
Language
English
Journal language
English
Abstract in English
The aim of this study was to investigate the clinical efficacy of vanadium complexes on triglycerides (TG), total cholesterol (Chol), uric acid (UA), urea (U), and antioxidant parameters: nonenzymatic (FRAP-ferric reducing ability of plasma, and reduced glutathione-GSH) and enzymatic (glutathione peroxidase-GPx, catalase-CAT, and GPx/CAT ratio) activity in the plasma of healthy male Wistar rats. Three vanadium complexes: [VO(bpy)2]SO4·2H2O, [VO(4,4 Me2bpy)2]SO4·2H2O, and Na[VO(O2)2(bpy)]·8H2O are administered by gavage during 5 weeks in two different diets such as control (C) and high fatty (F) diets. Changes of biochemical and antioxidants parameters are measured in plasma. All three vanadium complexes statistically decrease the body mass growth in comparison to the control and fatty diet. In plasma GSH was statistically increased in all vanadium complexes-treated rats from control and fatty group in comparison to only control group. Calculated GPX/CAT ratio was the highest in the control group in comparison to others.
Affiliation
Wydział Chemii : Zakład Chemii NieorganicznejWydział Farmaceutyczny : Zakład RadioligandówWydział Farmaceutyczny : Zakład BromatologiiWydział Farmaceutyczny : Zakład Chemii Bioorganicznej
Scopus© citations
22
| cris.lastimport.wos | 2024-04-10T02:48:59Z | |
| dc.abstract.en | The aim of this study was to investigate the clinical efficacy of vanadium complexes on triglycerides (TG), total cholesterol (Chol), uric acid (UA), urea (U), and antioxidant parameters: nonenzymatic (FRAP-ferric reducing ability of plasma, and reduced glutathione-GSH) and enzymatic (glutathione peroxidase-GPx, catalase-CAT, and GPx/CAT ratio) activity in the plasma of healthy male Wistar rats. Three vanadium complexes: [VO(bpy)2]SO4·2H2O, [VO(4,4 Me2bpy)2]SO4·2H2O, and Na[VO(O2)2(bpy)]·8H2O are administered by gavage during 5 weeks in two different diets such as control (C) and high fatty (F) diets. Changes of biochemical and antioxidants parameters are measured in plasma. All three vanadium complexes statistically decrease the body mass growth in comparison to the control and fatty diet. In plasma GSH was statistically increased in all vanadium complexes-treated rats from control and fatty group in comparison to only control group. Calculated GPX/CAT ratio was the highest in the control group in comparison to others. | pl |
| dc.affiliation | Wydział Chemii : Zakład Chemii Nieorganicznej | pl |
| dc.affiliation | Wydział Farmaceutyczny : Zakład Radioligandów | pl |
| dc.affiliation | Wydział Farmaceutyczny : Zakład Bromatologii | pl |
| dc.affiliation | Wydział Farmaceutyczny : Zakład Chemii Bioorganicznej | pl |
| dc.contributor.author | Francik, Renata - 129384 | pl |
| dc.contributor.author | Krośniak, Mirosław - 130417 | pl |
| dc.contributor.author | Barlik, Mateusz | pl |
| dc.contributor.author | Kudła, Agnieszka | pl |
| dc.contributor.author | Gryboś, Ryszard - 128193 | pl |
| dc.contributor.author | Librowski, Tadeusz - 130669 | pl |
| dc.date.accession | 2019-03-27 | pl |
| dc.date.accessioned | 2019-03-27T08:50:11Z | |
| dc.date.available | 2019-03-27T08:50:11Z | |
| dc.date.issued | 2011 | pl |
| dc.date.openaccess | 0 | |
| dc.description.accesstime | w momencie opublikowania | |
| dc.description.additional | Bibliogr. 206316-7 - 206316-8. | pl |
| dc.description.version | ostateczna wersja wydawcy | |
| dc.description.volume | 2011 | pl |
| dc.identifier.articleid | 206316 | pl |
| dc.identifier.doi | 10.1155/2011/206316 | pl |
| dc.identifier.eissn | 1687-479X | pl |
| dc.identifier.issn | 1565-3633 | pl |
| dc.identifier.project | ROD UJ / OP | pl |
| dc.identifier.uri | https://ruj.uj.edu.pl/xmlui/handle/item/71493 | |
| dc.identifier.weblink | https://www.hindawi.com/journals/bca/2011/206316/ | pl |
| dc.language | eng | pl |
| dc.language.container | eng | pl |
| dc.rights | Udzielam licencji. Uznanie autorstwa 3.0 | * |
| dc.rights.licence | CC-BY | |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/legalcode | * |
| dc.share.type | otwarte czasopismo | |
| dc.subtype | Article | pl |
| dc.title | Impact of vanadium complexes treatment on the oxidative stress factors in Wistar rats plasma | pl |
| dc.title.journal | Bioinorganic Chemistry and Applications | pl |
| dc.type | JournalArticle | pl |
| dspace.entity.type | Publication |
cris.lastimport.wos
2024-04-10T02:48:59Z dc.abstract.enpl
The aim of this study was to investigate the clinical efficacy of vanadium complexes on triglycerides (TG), total cholesterol
(Chol), uric acid (UA), urea (U), and antioxidant parameters: nonenzymatic (FRAP-ferric reducing ability of plasma, and
reduced glutathione-GSH) and enzymatic (glutathione peroxidase-GPx, catalase-CAT, and GPx/CAT ratio) activity in the
plasma of healthy male Wistar rats. Three vanadium complexes: [VO(bpy)2]SO4·2H2O, [VO(4,4
Me2bpy)2]SO4·2H2O, and
Na[VO(O2)2(bpy)]·8H2O are administered by gavage during 5 weeks in two different diets such as control (C) and high fatty (F)
diets. Changes of biochemical and antioxidants parameters are measured in plasma. All three vanadium complexes statistically
decrease the body mass growth in comparison to the control and fatty diet. In plasma GSH was statistically increased in all
vanadium complexes-treated rats from control and fatty group in comparison to only control group. Calculated GPX/CAT ratio
was the highest in the control group in comparison to others. dc.affiliationpl
Wydział Chemii : Zakład Chemii Nieorganicznej dc.affiliationpl
Wydział Farmaceutyczny : Zakład Radioligandów dc.affiliationpl
Wydział Farmaceutyczny : Zakład Bromatologii dc.affiliationpl
Wydział Farmaceutyczny : Zakład Chemii Bioorganicznej dc.contributor.authorpl
Francik, Renata - 129384 dc.contributor.authorpl
Krośniak, Mirosław - 130417 dc.contributor.authorpl
Barlik, Mateusz dc.contributor.authorpl
Kudła, Agnieszka dc.contributor.authorpl
Gryboś, Ryszard - 128193 dc.contributor.authorpl
Librowski, Tadeusz - 130669 dc.date.accessionpl
2019-03-27 dc.date.accessioned
2019-03-27T08:50:11Z dc.date.available
2019-03-27T08:50:11Z dc.date.issuedpl
2011 dc.date.openaccess
0 dc.description.accesstime
w momencie opublikowania dc.description.additionalpl
Bibliogr. 206316-7 - 206316-8. dc.description.version
ostateczna wersja wydawcy dc.description.volumepl
2011 dc.identifier.articleidpl
206316 dc.identifier.doipl
10.1155/2011/206316 dc.identifier.eissnpl
1687-479X dc.identifier.issnpl
1565-3633 dc.identifier.projectpl
ROD UJ / OP dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/71493 dc.identifier.weblinkpl
https://www.hindawi.com/journals/bca/2011/206316/ dc.languagepl
eng dc.language.containerpl
eng dc.rights*
Udzielam licencji. Uznanie autorstwa 3.0 dc.rights.licence
CC-BY dc.rights.uri*
http://creativecommons.org/licenses/by/3.0/legalcode dc.share.type
otwarte czasopismo dc.subtypepl
Article dc.titlepl
Impact of vanadium complexes treatment on the oxidative stress factors in Wistar rats plasma dc.title.journalpl
Bioinorganic Chemistry and Applications dc.typepl
JournalArticle dspace.entity.type
Publication Affiliations
No affiliation
Francik, Renata
Krośniak, Mirosław
Barlik, Mateusz
Kudła, Agnieszka
Gryboś, Ryszard
Librowski, Tadeusz
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