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Preoperative mediastinal lymph node staging for non-small cell lung cancer : 2014 update of the 2007 ESTS guidelines
lung cancer
preoperative staging
surgical staging
endoscopic staging
Accurate preoperative staging and restaging of mediastinal lymph nodes in patients with potentially resectable non-small cell lung cancer (NSCLC) is of paramount importance. In 2007, the European Society of Thoracic Surgeons (ESTS) published an algorithm on preoperative mediastinal staging integrating imaging, endoscopic and surgical techniques. Over the last years more evidence of the different mediastinal staging technique has become available. Therefore, a revision of the ESTS guidelines was needed. In case of CT-enlarged or PET-positive mediastinal lymph nodes, tissue confirmation is indicated. Endosonography (EBUS/EUS) with fine needle aspiration is the first choice (when available) since it is minimally invasive and has a high sensitivity to rule in mediastinal nodal disease. If negative, surgical staging with nodal dissection or biopsy is indicated. Video-assisted mediastinoscopy is preferred over mediastinoscopy. The combined use of endoscopic staging and surgical staging results in the highest accuracy. When there are no enlarged lymph nodes on CT and when there is no uptake in lymph nodes on PET or PET-CT, direct surgical resection with systematic nodal dissection is indicated for tumors ≤3 cm located in the outer third of the lung. In central tumors or N1 nodes, preoperative mediastinal staging is indicated. The choice between endoscopic staging with EBUS/EUS and fine needle aspiration or video-assisted mediastinoscopy depends on local expertise to adhere to minimal requirements for staging. For tumors larger than 3 cm, preoperative mediastinal staging is advised, mainly in adenocarcinoma with high SUV uptake.
cris.lastimport.wos | 2024-04-09T20:33:27Z | |
dc.abstract.en | Accurate preoperative staging and restaging of mediastinal lymph nodes in patients with potentially resectable non-small cell lung cancer (NSCLC) is of paramount importance. In 2007, the European Society of Thoracic Surgeons (ESTS) published an algorithm on preoperative mediastinal staging integrating imaging, endoscopic and surgical techniques. Over the last years more evidence of the different mediastinal staging technique has become available. Therefore, a revision of the ESTS guidelines was needed. In case of CT-enlarged or PET-positive mediastinal lymph nodes, tissue confirmation is indicated. Endosonography (EBUS/EUS) with fine needle aspiration is the first choice (when available) since it is minimally invasive and has a high sensitivity to rule in mediastinal nodal disease. If negative, surgical staging with nodal dissection or biopsy is indicated. Video-assisted mediastinoscopy is preferred over mediastinoscopy. The combined use of endoscopic staging and surgical staging results in the highest accuracy. When there are no enlarged lymph nodes on CT and when there is no uptake in lymph nodes on PET or PET-CT, direct surgical resection with systematic nodal dissection is indicated for tumors ≤3 cm located in the outer third of the lung. In central tumors or N1 nodes, preoperative mediastinal staging is indicated. The choice between endoscopic staging with EBUS/EUS and fine needle aspiration or video-assisted mediastinoscopy depends on local expertise to adhere to minimal requirements for staging. For tumors larger than 3 cm, preoperative mediastinal staging is advised, mainly in adenocarcinoma with high SUV uptake. | pl |
dc.affiliation | Wydział Nauk o Zdrowiu : Instytut Fizjoterapii | pl |
dc.cm.date | 2020-01-07 | |
dc.cm.id | 72441 | |
dc.contributor.author | De Leyn, Paul | pl |
dc.contributor.author | Dooms, Christophe | pl |
dc.contributor.author | Kużdżał, Jarosław - 199984 | pl |
dc.contributor.author | Lardinois, Didier | pl |
dc.contributor.author | Passlick, Bernward | pl |
dc.contributor.author | Rami-Porta, Ramon | pl |
dc.contributor.author | Turna, Akif | pl |
dc.contributor.author | Van Schil, Paul | pl |
dc.contributor.author | Venuta, Frederico | pl |
dc.contributor.author | Waller, David | pl |
dc.contributor.author | Weder, Walter | pl |
dc.contributor.author | Zieliński, Marcin | pl |
dc.date.accessioned | 2020-01-17T08:48:29Z | |
dc.date.available | 2020-01-17T08:48:29Z | |
dc.date.issued | 2014 | pl |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.number | 4 | pl |
dc.description.physical | 225-233 | pl |
dc.description.points | 5 | pl |
dc.description.publication | 0,95 | pl |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 3 | pl |
dc.identifier.doi | 10.3978/j.issn.2218-6751.2014.08.05 | pl |
dc.identifier.eissn | 2226-4477 | pl |
dc.identifier.issn | 2218-6751 | pl |
dc.identifier.project | ROD UJ / OP | pl |
dc.identifier.uri | https://ruj.uj.edu.pl/xmlui/handle/item/135471 | |
dc.language | eng | pl |
dc.language.container | eng | pl |
dc.rights | Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa | * |
dc.rights.licence | CC-BY-NC-ND | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl | * |
dc.share.type | otwarte czasopismo | |
dc.subject.en | lung cancer | pl |
dc.subject.en | preoperative staging | pl |
dc.subject.en | surgical staging | pl |
dc.subject.en | endoscopic staging | pl |
dc.subtype | ReviewArticle | pl |
dc.title | Preoperative mediastinal lymph node staging for non-small cell lung cancer : 2014 update of the 2007 ESTS guidelines | pl |
dc.title.journal | Translational Lung Cancer Research | pl |
dc.type | JournalArticle | pl |
dspace.entity.type | Publication |
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