Whole-body low-dose computed tomography (WBLDCT) in assessment of patients with multiple myeloma : pilot study and standard imaging protocol suggestion

2017
journal article
article
15
cris.lastimport.wos2024-04-09T18:58:31Z
dc.abstract.enBACKGROUND: For decades, the main imaging tool in multiple myeloma (MM) patients was plain radiography. However, computed tomography (CT) has been included in the updated criteria of MM. The main disadvantage of CT is a considerably high radiation dose. Therefore, low-dose CT protocols could be a solution. The aim of the study was to (1) preliminarily analyse the usefulness of Whole-Body Low-Dose CT (WBLDCT) in the evaluation of patients with MM and (2) to make adjustments in the standard CT imaging protocol. MATERIAL AND METHODS: In 41 patients with MM, WBLDCT was performed. The following parameters were used: detector configuration - 80×0.5 mm, scanning range in a single spiral acquisition from the skull to the proximal femoral bones, tube voltage - 120 kVp, current tube time product - 86 mAs, slice thickness 1 mm. Two sets of axial images were reconstructed for bone and soft tissue assessment, respectively. Secondary coronal and sagittal reconstructions were generated. Typical MM features were analysed and qualitatively compared with radiography results. RESULTS: A potentially increased sensitivity of CT, as compared to radiography, in detecting lytic foci obscured by other structures or with a small degree of destruction was seen. A potentially increased specificity of CT was found in detecting cases of small foci suspicious of lytic lesions on skull radiographs, seen as arachnoid granulations fovea in CT. The following radiation parameters were recorded: max. CTDIvol - 7.4 mGy and DLP - 660-810 mGy×cm. WBLDCT was much shorter and more convenient to patients. CONCLUSIONS: WBLDCT may become a valuable part of the assessment of MM features at a much lower radiation dose compared to standard CT protocols. It has a potential ability to increase diagnostic accuracy compared to radiography.pl
dc.affiliationWydział Lekarski : Zakład Radiologiipl
dc.affiliationWydział Lekarski : Klinika Hematologiipl
dc.cm.id83375
dc.contributor.authorChrzan, Robert - 129018 pl
dc.contributor.authorJurczyszyn, Artur - 255153 pl
dc.contributor.authorUrbanik, Andrzej - 133713 pl
dc.date.accessioned2017-07-05T06:43:23Z
dc.date.available2017-07-05T06:43:23Z
dc.date.issued2017pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 363pl
dc.description.physical356-363pl
dc.description.points15pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume82pl
dc.identifier.doi10.12659/PJR.901742pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.projectROD UJ / Ppl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/42347
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode*
dc.share.typeotwarte czasopismo
dc.subject.enmultiple myelomapl
dc.subject.enradiation dosagepl
dc.subject.entomographypl
dc.subject.enspiral computedpl
dc.subject.enwhole body imagingpl
dc.subtypeArticlepl
dc.titleWhole-body low-dose computed tomography (WBLDCT) in assessment of patients with multiple myeloma : pilot study and standard imaging protocol suggestionpl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T18:58:31Z
dc.abstract.enpl
BACKGROUND: For decades, the main imaging tool in multiple myeloma (MM) patients was plain radiography. However, computed tomography (CT) has been included in the updated criteria of MM. The main disadvantage of CT is a considerably high radiation dose. Therefore, low-dose CT protocols could be a solution. The aim of the study was to (1) preliminarily analyse the usefulness of Whole-Body Low-Dose CT (WBLDCT) in the evaluation of patients with MM and (2) to make adjustments in the standard CT imaging protocol. MATERIAL AND METHODS: In 41 patients with MM, WBLDCT was performed. The following parameters were used: detector configuration - 80×0.5 mm, scanning range in a single spiral acquisition from the skull to the proximal femoral bones, tube voltage - 120 kVp, current tube time product - 86 mAs, slice thickness 1 mm. Two sets of axial images were reconstructed for bone and soft tissue assessment, respectively. Secondary coronal and sagittal reconstructions were generated. Typical MM features were analysed and qualitatively compared with radiography results. RESULTS: A potentially increased sensitivity of CT, as compared to radiography, in detecting lytic foci obscured by other structures or with a small degree of destruction was seen. A potentially increased specificity of CT was found in detecting cases of small foci suspicious of lytic lesions on skull radiographs, seen as arachnoid granulations fovea in CT. The following radiation parameters were recorded: max. CTDIvol - 7.4 mGy and DLP - 660-810 mGy×cm. WBLDCT was much shorter and more convenient to patients. CONCLUSIONS: WBLDCT may become a valuable part of the assessment of MM features at a much lower radiation dose compared to standard CT protocols. It has a potential ability to increase diagnostic accuracy compared to radiography.
dc.affiliationpl
Wydział Lekarski : Zakład Radiologii
dc.affiliationpl
Wydział Lekarski : Klinika Hematologii
dc.cm.id
83375
dc.contributor.authorpl
Chrzan, Robert - 129018
dc.contributor.authorpl
Jurczyszyn, Artur - 255153
dc.contributor.authorpl
Urbanik, Andrzej - 133713
dc.date.accessioned
2017-07-05T06:43:23Z
dc.date.available
2017-07-05T06:43:23Z
dc.date.issuedpl
2017
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 363
dc.description.physicalpl
356-363
dc.description.pointspl
15
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
82
dc.identifier.doipl
10.12659/PJR.901742
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.projectpl
ROD UJ / P
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/42347
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode
dc.share.type
otwarte czasopismo
dc.subject.enpl
multiple myeloma
dc.subject.enpl
radiation dosage
dc.subject.enpl
tomography
dc.subject.enpl
spiral computed
dc.subject.enpl
whole body imaging
dc.subtypepl
Article
dc.titlepl
Whole-body low-dose computed tomography (WBLDCT) in assessment of patients with multiple myeloma : pilot study and standard imaging protocol suggestion
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

* The migration of download and view statistics prior to the date of April 8, 2024 is in progress.

Views
4
Views per month
Views per city
Katowice
1
Piaseczno
1
Warsaw
1
Downloads
chrzan_jurczyszyn_urbanik_whole-body_low-dose_computed_tomography_wbldct_2017.pdf
31